1. Polymer synthesis and properties of polymers in solution

– Self-assembly of telechelic amphiphilic polymers in water

– Thermoresponsive polymers

– Cyclic thermoresponsive polymers

2. Interactions of Amphipol (amphiphilic polymers) and proteins

The thermal stability of immunoglobulin G (IgG) in water was monitored by differential scanning calorimetry (DSC), dynamic light scattering (DLS), and fluorescence correlation spectroscopy (FCS) in the presence of an amphiphilic polymer (amphipol). IgG did not aggregate upon heating up to 75 °C in the presence of polymer unlike the situation in the absence of polymer. The mixed solutions remained free of aggregates upon cooling. These results indicate that amphipols facilitate the handling of IgG under stress conditions and, possibly, during protein refolding.
The Thermally Induced Aggregation of Immunoglobulin G in Solution is Prevented by Amphipols
Dewang Ma, Nicolas Martin, Amaury Herbet, Dider Boquet, Christophe Tribet, and Françoise M. Winnik, Chem. Lett. 2012, 41, 1380.

3. Responsive nanoparticles

4. Layer-by-layer studies

– Chitosan-Hyaluronic acid layer by layer

– Pro-drug polyelectrolytes multilayers

5.Synthesis, functionalization and characterization of Quantum dots